8c8s: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
Line 1: Line 1:
'''Unreleased structure'''


The entry 8c8s is ON HOLD  until Paper Publication
==Crystal structure of human DNA cross-link repair 1A in complex with hydroxamic acid inhibitor (compound 21).==
 
<StructureSection load='8c8s' size='340' side='right'caption='[[8c8s]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
Authors: Yosaatmadja, Y., Newman, J.A., Baddock, H.T., Bielinski, M., von Delft, F., Bountra, C., McHugh, P.J., Schofield, C.J., Gileadi, O.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8c8s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8C8S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8C8S FirstGlance]. <br>
Description: Crystal structure of human DNA cross-link repair 1A in complex with hydroxamic acid inhibitor (compound 21).
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=U2O:(2~{R})-3-[6-chloranyl-2-(prop-2-enylamino)quinazolin-4-yl]-2-methyl-~{N}-oxidanyl-propanamide'>U2O</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Gileadi, O]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8c8s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8c8s OCA], [https://pdbe.org/8c8s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8c8s RCSB], [https://www.ebi.ac.uk/pdbsum/8c8s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8c8s ProSAT]</span></td></tr>
[[Category: Newman, J.A]]
</table>
[[Category: Yosaatmadja, Y]]
== Function ==
[[Category: Bielinski, M]]
[https://www.uniprot.org/uniprot/DCR1A_HUMAN DCR1A_HUMAN] May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.<ref>PMID:15542852</ref>
[[Category: Mchugh, P.J]]
== References ==
[[Category: Von Delft, F]]
<references/>
[[Category: Bountra, C]]
__TOC__
[[Category: Schofield, C.J]]
</StructureSection>
[[Category: Baddock, H.T]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Baddock HT]]
[[Category: Bielinski M]]
[[Category: Bountra C]]
[[Category: Gileadi O]]
[[Category: McHugh PJ]]
[[Category: Newman JA]]
[[Category: Schofield CJ]]
[[Category: Yosaatmadja Y]]
[[Category: Von Delft F]]
Retrieved from "https://proteopedia.org/8c8s"