7nl8: Difference between revisions
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==Crystal structure of a shortened IpgC variant in complex with 3-methylbenzohydrazide== | ==Crystal structure of a shortened IpgC variant in complex with 3-methylbenzohydrazide== | ||
<StructureSection load='7nl8' size='340' side='right'caption='[[7nl8]]' scene=''> | <StructureSection load='7nl8' size='340' side='right'caption='[[7nl8]], [[Resolution|resolution]] 1.59Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NL8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NL8 FirstGlance]. <br> | <table><tr><td colspan='2'>[[7nl8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NL8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NL8 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nl8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nl8 OCA], [https://pdbe.org/7nl8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nl8 RCSB], [https://www.ebi.ac.uk/pdbsum/7nl8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nl8 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.59Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=45L:3-METHYLBENZOHYDRAZIDE'>45L</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nl8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nl8 OCA], [https://pdbe.org/7nl8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nl8 RCSB], [https://www.ebi.ac.uk/pdbsum/7nl8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nl8 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/IPGC_SHIFL IPGC_SHIFL] Assists the correct folding of nascent IpaB. Once it is bound to IpaB, it binds to IpaC and impedes their premature association that would lead to their degradation in the absence of IpcG. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Shigella flexneri]] | |||
[[Category: Gardonyi M]] | [[Category: Gardonyi M]] | ||
[[Category: Heine A]] | [[Category: Heine A]] | ||
[[Category: Klebe G]] | [[Category: Klebe G]] | ||
Latest revision as of 12:36, 1 February 2024
Crystal structure of a shortened IpgC variant in complex with 3-methylbenzohydrazide
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