7nnz: Difference between revisions
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==Crystal structure of Mycobacterium tuberculosis ArgF in complex with 5-methyl-4-phenylthiazol-2-amine.== | ==Crystal structure of Mycobacterium tuberculosis ArgF in complex with 5-methyl-4-phenylthiazol-2-amine.== | ||
<StructureSection load='7nnz' size='340' side='right'caption='[[7nnz]]' scene=''> | <StructureSection load='7nnz' size='340' side='right'caption='[[7nnz]], [[Resolution|resolution]] 1.68Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NNZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NNZ FirstGlance]. <br> | <table><tr><td colspan='2'>[[7nnz]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NNZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NNZ FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nnz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nnz OCA], [https://pdbe.org/7nnz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nnz RCSB], [https://www.ebi.ac.uk/pdbsum/7nnz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nnz ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.68Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=PTZ:5-methyl-4-phenyl-1,3-thiazol-2-amine'>PTZ</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nnz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nnz OCA], [https://pdbe.org/7nnz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nnz RCSB], [https://www.ebi.ac.uk/pdbsum/7nnz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nnz ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/OTC_MYCTU OTC_MYCTU] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity).[HAMAP-Rule:MF_01109] | |||
==See Also== | |||
*[[Ornithine carbamoyltransferase 3D structures|Ornithine carbamoyltransferase 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Mycobacterium tuberculosis H37Rv]] | |||
[[Category: Blundell TL]] | [[Category: Blundell TL]] | ||
[[Category: Burgess A]] | [[Category: Burgess A]] | ||
Latest revision as of 12:37, 1 February 2024
Crystal structure of Mycobacterium tuberculosis ArgF in complex with 5-methyl-4-phenylthiazol-2-amine.
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