7p9o: Difference between revisions

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<StructureSection load='7p9o' size='340' side='right'caption='[[7p9o]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='7p9o' size='340' side='right'caption='[[7p9o]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7p9o]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P9O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P9O FirstGlance]. <br>
<table><tr><td colspan='2'>[[7p9o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P9O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P9O FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0Y0:5-{[(3S)-3-AMINO-3-CARBOXYPROPYL]AMINO}-5-DEOXYADENOSINE'>0Y0</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.095&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[6qdx|6qdx]], [[7p8q|7p8q]], [[7p9i|7p9i]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0Y0:5-{[(3S)-3-AMINO-3-CARBOXYPROPYL]AMINO}-5-DEOXYADENOSINE'>0Y0</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/23S_rRNA_(adenine(2030)-N(6))-methyltransferase 23S rRNA (adenine(2030)-N(6))-methyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.266 2.1.1.266] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p9o OCA], [https://pdbe.org/7p9o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p9o RCSB], [https://www.ebi.ac.uk/pdbsum/7p9o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p9o ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p9o OCA], [https://pdbe.org/7p9o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p9o RCSB], [https://www.ebi.ac.uk/pdbsum/7p9o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p9o ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/RLMJ_ECOLI RLMJ_ECOLI]] Specifically methylates the adenine in position 2030 of 23S rRNA. Nascent 23S rRNA seems to be the natural substrate. Appears to be not necessary for ribosome assembly. Seems to be required for the utilization of extracellular DNA as the sole source of carbon and energy.<ref>PMID:16707682</ref> <ref>PMID:22847818</ref>
[https://www.uniprot.org/uniprot/RLMJ_ECOLI RLMJ_ECOLI] Specifically methylates the adenine in position 2030 of 23S rRNA. Nascent 23S rRNA seems to be the natural substrate. Appears to be not necessary for ribosome assembly. Seems to be required for the utilization of extracellular DNA as the sole source of carbon and energy.<ref>PMID:16707682</ref> <ref>PMID:22847818</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Barraud, P]]
[[Category: Barraud P]]
[[Category: Catala, M]]
[[Category: Catala M]]
[[Category: Meynier, V]]
[[Category: Meynier V]]
[[Category: Oerum, S]]
[[Category: Oerum S]]
[[Category: Tisne, C]]
[[Category: Tisne C]]
[[Category: Bisubstrate analogue]]
[[Category: Conjugate analogue]]
[[Category: M6a]]
[[Category: Methyltransferase]]
[[Category: Rlmj]]
[[Category: Rna binding]]
[[Category: Rna binding protein]]
[[Category: Rna mtase]]
[[Category: Rna recognition]]
[[Category: Sam analogue]]
[[Category: Sam conjugate]]