7pgm: Difference between revisions

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<StructureSection load='7pgm' size='340' side='right'caption='[[7pgm]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='7pgm' size='340' side='right'caption='[[7pgm]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7pgm]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PGM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7PGM FirstGlance]. <br>
<table><tr><td colspan='2'>[[7pgm]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PGM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7PGM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IDS:2-O-SULFO-ALPHA-L-IDOPYRANURONIC+ACID'>IDS</scene>, <scene name='pdbligand=SGN:N,O6-DISULFO-GLUCOSAMINE'>SGN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IDS:2-O-SULFO-ALPHA-L-IDOPYRANURONIC+ACID'>IDS</scene>, <scene name='pdbligand=SGN:N,O6-DISULFO-GLUCOSAMINE'>SGN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7pgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7pgm OCA], [https://pdbe.org/7pgm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7pgm RCSB], [https://www.ebi.ac.uk/pdbsum/7pgm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7pgm ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7pgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7pgm OCA], [https://pdbe.org/7pgm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7pgm RCSB], [https://www.ebi.ac.uk/pdbsum/7pgm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7pgm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/HHIP_HUMAN HHIP_HUMAN]] Modulates hedgehog signaling in several cell types including brain and lung through direct interaction with members of the hedgehog family.<ref>PMID:11472839</ref> <ref>PMID:19561609</ref>
[https://www.uniprot.org/uniprot/HHIP_HUMAN HHIP_HUMAN] Modulates hedgehog signaling in several cell types including brain and lung through direct interaction with members of the hedgehog family.<ref>PMID:11472839</ref> <ref>PMID:19561609</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bishop, B]]
[[Category: Bishop B]]
[[Category: Covey, D F]]
[[Category: Covey DF]]
[[Category: Dubey, R]]
[[Category: Dubey R]]
[[Category: Gilbert, R J.C]]
[[Category: El Omari K]]
[[Category: Griffiths, S C]]
[[Category: Gilbert RJC]]
[[Category: Iverson, E J]]
[[Category: Griffiths SC]]
[[Category: Malinuskas, T]]
[[Category: Iverson EJ]]
[[Category: Omari, K El]]
[[Category: Malinuskas T]]
[[Category: Qian, M]]
[[Category: Qian M]]
[[Category: Rohatgi, R]]
[[Category: Rohatgi R]]
[[Category: Schwab, R A]]
[[Category: Schwab RA]]
[[Category: Siebold, C]]
[[Category: Siebold C]]
[[Category: Cholesterol]]
[[Category: Glycosaminoglycan]]
[[Category: Hedgehog]]
[[Category: Hhip]]
[[Category: Morphogen]]
[[Category: Palmitate]]
[[Category: Secreted]]
[[Category: Signaling protein]]
[[Category: Signalling]]