5qbz: Difference between revisions
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==Crystal structure of human Cathepsin-S with bound ligand== | ==Crystal structure of human Cathepsin-S with bound ligand== | ||
<StructureSection load='5qbz' size='340' side='right'caption='[[5qbz]]' scene=''> | <StructureSection load='5qbz' size='340' side='right'caption='[[5qbz]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QBZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QBZ FirstGlance]. <br> | <table><tr><td colspan='2'>[[5qbz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QBZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QBZ FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qbz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qbz OCA], [https://pdbe.org/5qbz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qbz RCSB], [https://www.ebi.ac.uk/pdbsum/5qbz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qbz ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B8Y:N-{[2-chloro-5-(4-{3-[4-(6-chloro-3-methyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl]propyl}-3-oxo-3,4-dihydropyrazin-2-yl)phenyl]methyl}-4-fluorobenzamide'>B8Y</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qbz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qbz OCA], [https://pdbe.org/5qbz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qbz RCSB], [https://www.ebi.ac.uk/pdbsum/5qbz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qbz ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/CATS_HUMAN CATS_HUMAN] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. | |||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Ameriks MK]] | [[Category: Ameriks MK]] | ||
