1ahq: Difference between revisions

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<StructureSection load='1ahq' size='340' side='right'caption='[[1ahq]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='1ahq' size='340' side='right'caption='[[1ahq]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ahq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acaca Acaca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AHQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AHQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ahq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acanthamoeba_castellanii Acanthamoeba castellanii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AHQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AHQ FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ahq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ahq OCA], [https://pdbe.org/1ahq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ahq RCSB], [https://www.ebi.ac.uk/pdbsum/1ahq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ahq ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ahq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ahq OCA], [https://pdbe.org/1ahq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ahq RCSB], [https://www.ebi.ac.uk/pdbsum/1ahq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ahq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/ACTP_ACACA ACTP_ACACA]] Forms a one to one complex with monomeric actin. Can regulate the pool available for polymerization. Severs actin filaments in a dose-dependent manner.  
[https://www.uniprot.org/uniprot/ACTP_ACACA ACTP_ACACA] Forms a one to one complex with monomeric actin. Can regulate the pool available for polymerization. Severs actin filaments in a dose-dependent manner.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ahq ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ahq ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Actophorin is a member of the actin-depolymerizing factor/cofilin family. It severs actin filaments and sequesters actin monomers. The crystal structure of actophorin will help to elucidate actin-ADF/cofilin interactions.
Crystal structure of the actin-binding protein actophorin from Acanthamoeba.,Leonard SA, Gittis AG, Petrella EC, Pollard TD, Lattman EE Nat Struct Biol. 1997 May;4(5):369-73. PMID:9145107<ref>PMID:9145107</ref>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 1ahq" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Acaca]]
[[Category: Acanthamoeba castellanii]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Gittis, A G]]
[[Category: Gittis AG]]
[[Category: Lattman, E E]]
[[Category: Lattman EE]]
[[Category: Leonard, S A]]
[[Category: Leonard SA]]
[[Category: Petrella, E C]]
[[Category: Petrella EC]]
[[Category: Pollard, T D]]
[[Category: Pollard TD]]
[[Category: Actin binding protein]]
[[Category: Actophorin]]

Latest revision as of 06:30, 7 February 2024

RECOMBINANT ACTOPHORIN

1ahq, resolution 2.30Å

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