5qhs: Difference between revisions
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<StructureSection load='5qhs' size='340' side='right'caption='[[5qhs]], [[Resolution|resolution]] 1.95Å' scene=''> | <StructureSection load='5qhs' size='340' side='right'caption='[[5qhs]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5qhs]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QHS OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5qhs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QHS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QHS FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GQV:1-methyl-3-oxidanyl-pyridin-2-one'>GQV</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GQV:1-methyl-3-oxidanyl-pyridin-2-one'>GQV</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qhs OCA], [https://pdbe.org/5qhs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qhs RCSB], [https://www.ebi.ac.uk/pdbsum/5qhs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qhs ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/FA83B_HUMAN FA83B_HUMAN] Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. May activate both the EGFR itself and downstream RAS/MAPK and PI3K/AKT/TOR signaling cascades.<ref>PMID:22886302</ref> <ref>PMID:23676467</ref> <ref>PMID:23912460</ref> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith CH]] | ||
[[Category: Bountra | [[Category: Bountra C]] | ||
[[Category: Bufton | [[Category: Bufton JC]] | ||
[[Category: Bullock | [[Category: Bullock AN]] | ||
[[Category: Collins | [[Category: Collins P]] | ||
[[Category: Douangamath A]] | |||
[[Category: Douangamath | [[Category: Edwards A]] | ||
[[Category: Edwards | [[Category: Fox AE]] | ||
[[Category: Fox | [[Category: Krojer T]] | ||
[[Category: Krojer | [[Category: Pinkas DM]] | ||
[[Category: Pinkas | [[Category: Talon R]] | ||
[[Category: Talon | [[Category: Zhang R]] | ||
[[Category: Zhang | [[Category: Von Delft F]] | ||
[[Category: | |||
Latest revision as of 08:54, 7 February 2024
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FF000014a
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