8y0s: Difference between revisions
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==Crystal structure of metallo-beta-lactamse, IMP-1, complexed with a quinolinone-based inhibitor== | |||
<StructureSection load='8y0s' size='340' side='right'caption='[[8y0s]], [[Resolution|resolution]] 2.75Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8y0s]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Serratia_marcescens Serratia marcescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Y0S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Y0S FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1LXO:3-[2-azanyl-5-[2-cyclohexylethyl-[3-(4-methylphenoxy)propyl]amino]phenyl]propanoic+acid'>A1LXO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
[[Category: Guo | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8y0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8y0s OCA], [https://pdbe.org/8y0s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8y0s RCSB], [https://www.ebi.ac.uk/pdbsum/8y0s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8y0s ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/BLAB_SERMA BLAB_SERMA] Confers resistance to imipenem and broad-spectrum beta-lactams. Also hydrolyzes carbapenems. | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Serratia marcescens]] | |||
[[Category: Guo Y]] | |||
[[Category: Hoshino T]] | |||
[[Category: Kamo T]] | |||
[[Category: Kondo S]] | |||
[[Category: Kuroda K]] | |||
[[Category: Nimura S]] | |||
[[Category: Nukaga M]] | |||
Latest revision as of 07:24, 14 February 2024
Crystal structure of metallo-beta-lactamse, IMP-1, complexed with a quinolinone-based inhibitor
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