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'''Crystal Structure of YfdW protein from E. coli''' | '''Crystal Structure of YfdW protein from E. coli''' | ||
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[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]] | [[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]] | ||
[[Category: Shapiro, L.]] | [[Category: Shapiro, L.]] | ||
[[Category: | [[Category: Intertwined dimer]] | ||
[[Category: | [[Category: New york structural genomix research consortium]] | ||
[[Category: | [[Category: Nysgxrc]] | ||
[[Category: | [[Category: Protein structure initiative]] | ||
[[Category: | [[Category: Psi]] | ||
[[Category: | [[Category: Structural genomic]] | ||
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Revision as of 02:57, 3 May 2008
Crystal Structure of YfdW protein from E. coli
Overview
Crystal structures are reported for free and coenzyme A (CoA) bound forms of the YfdW protein from Escherichia coli, a representative type III CoA transferase. The structures reveal a two-domain protomer with interdomain connections forming a ring-like structure with a large central hole. Two protomers associate to form a highly intertwined dimer in which the hole of each ring is filled by the partner molecule. Each protomer binds a single CoA molecule and these CoA-binding sites are distant from one another in the dimer.
About this Structure
1Q7E is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
Structure of Escherichia coli YfdW, a type III CoA transferase., Gogos A, Gorman J, Shapiro L, Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):507-11. Epub 2004, Feb 25. PMID:14993676 Page seeded by OCA on Sat May 3 05:57:35 2008