1r8i: Difference between revisions

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<StructureSection load='1r8i' size='340' side='right'caption='[[1r8i]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='1r8i' size='340' side='right'caption='[[1r8i]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1r8i]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R8I OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1R8I FirstGlance]. <br>
<table><tr><td colspan='2'>[[1r8i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R8I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R8I FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trac ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1r8i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r8i OCA], [http://pdbe.org/1r8i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1r8i RCSB], [http://www.ebi.ac.uk/pdbsum/1r8i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1r8i ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r8i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r8i OCA], [https://pdbe.org/1r8i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r8i RCSB], [https://www.ebi.ac.uk/pdbsum/1r8i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r8i ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9L6G5_ECOLX Q9L6G5_ECOLX]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r8i ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r8i ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Type IV secretion systems mediate intercellular transfer of macro-molecules via a mechanism ancestrally related to that of bacterial conjugation machineries. TraC of the IncN plasmid pKM101 belongs to the VirB5 family of proteins, an essential component of most type IV secretion systems. Here, we present the structure of TraC. VirB5/TraC is a single domain protein, which consists of a three helix bundle and a loose globular appendage. Structure-based site-directed mutagenesis followed by functional studies indicates that VirB5 proteins participate in protein-protein interactions important for pilus assembly and function.
Structural and functional characterization of the VirB5 protein from the type IV secretion system encoded by the conjugative plasmid pKM101.,Yeo HJ, Yuan Q, Beck MR, Baron C, Waksman G Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15947-52. Epub 2003 Dec 12. PMID:14673074<ref>PMID:14673074</ref>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 1r8i" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Baron, C]]
[[Category: Baron C]]
[[Category: Beck, M R]]
[[Category: Beck MR]]
[[Category: Waksman, G]]
[[Category: Waksman G]]
[[Category: Yeo, H J]]
[[Category: Yeo H-J]]
[[Category: Yuan, Q]]
[[Category: Yuan Q]]
[[Category: Helical bundle]]
[[Category: Structural protein]]
[[Category: Trac]]
[[Category: Virb5]]

Latest revision as of 08:21, 14 February 2024

Crystal structure of TraC

1r8i, resolution 3.00Å

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