1y1s: Difference between revisions

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<StructureSection load='1y1s' size='340' side='right'caption='[[1y1s]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
<StructureSection load='1y1s' size='340' side='right'caption='[[1y1s]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1y1s]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y1S OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1Y1S FirstGlance]. <br>
<table><tr><td colspan='2'>[[1y1s]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y1S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y1S FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=URA:URACIL'>URA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1sj9|1sj9]], [[1ryz|1ryz]], [[1y1q|1y1q]], [[1y1r|1y1r]], [[1y1t|1y1t]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=URA:URACIL'>URA</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UDP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=99287 SALTY])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y1s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y1s OCA], [https://pdbe.org/1y1s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y1s RCSB], [https://www.ebi.ac.uk/pdbsum/1y1s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y1s ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Uridine_phosphorylase Uridine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.3 2.4.2.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1y1s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y1s OCA], [http://pdbe.org/1y1s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1y1s RCSB], [http://www.ebi.ac.uk/pdbsum/1y1s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1y1s ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/UDP_SALTY UDP_SALTY]] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity).  
[https://www.uniprot.org/uniprot/UDP_SALTY UDP_SALTY] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Salty]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
[[Category: Uridine phosphorylase]]
[[Category: Betzel C]]
[[Category: Betzel, C]]
[[Category: Dontsova MV]]
[[Category: Dontsova, M V]]
[[Category: Ealick SE]]
[[Category: Ealick, S E]]
[[Category: Gabdoulkhakov AG]]
[[Category: Gabdoulkhakov, A G]]
[[Category: Kachalova GS]]
[[Category: Kachalova, G S]]
[[Category: Mikhailov AM]]
[[Category: Mikhailov, A M]]
[[Category: Nucleoside phosphorylase]]
[[Category: Transferase]]

Latest revision as of 08:54, 14 February 2024

Crystal Structure of the Uridine Phosphorylase from Salmonella Typhimurium in Complex with Uracil and Sulfate Ion at 2.55A Resolution

1y1s, resolution 2.55Å

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