8cew: Difference between revisions

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'''Unreleased structure'''


The entry 8cew is ON HOLD  until Paper Publication
==Crystal structure of human DNA cross-link repair 1A in complex with N-hydroxyimide inhibitor H1==
 
<StructureSection load='8cew' size='340' side='right'caption='[[8cew]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8cew]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CEW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CEW FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=UFI:6-methoxy-2-oxidanyl-benzo[de]isoquinoline-1,3-dione'>UFI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8cew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8cew OCA], [https://pdbe.org/8cew PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8cew RCSB], [https://www.ebi.ac.uk/pdbsum/8cew PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8cew ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DCR1A_HUMAN DCR1A_HUMAN] May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.<ref>PMID:15542852</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Baddock HT]]
[[Category: Bielinski M]]
[[Category: Bountra C]]
[[Category: Gileadi O]]
[[Category: McHugh PJ]]
[[Category: Newman JA]]
[[Category: Schofield CJ]]
[[Category: Yosaatmadja Y]]
[[Category: Von Delft F]]
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