8q1s: Difference between revisions

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'''Unreleased structure'''


The entry 8q1s is ON HOLD  until Paper Publication
==Pathogenic mutations of human phosphorylation sites affect protein-protein interactions==
 
<StructureSection load='8q1s' size='340' side='right'caption='[[8q1s]], [[Resolution|resolution]] 3.23&Aring;' scene=''>
Authors: Roske, Y., Daumke, O., Rrustemi, T., Selbach, M.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8q1s]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Q1S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Q1S FirstGlance]. <br>
Description: Pathogenic mutations of human phosphorylation sites affect protein-protein interactions
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.23&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
[[Category: Selbach, M]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8q1s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8q1s OCA], [https://pdbe.org/8q1s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8q1s RCSB], [https://www.ebi.ac.uk/pdbsum/8q1s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8q1s ProSAT]</span></td></tr>
[[Category: Roske, Y]]
</table>
[[Category: Rrustemi, T]]
== Disease ==
[[Category: Daumke, O]]
[https://www.uniprot.org/uniprot/1433E_HUMAN 1433E_HUMAN] Distal 17p13.3 microdeletion syndrome;17p13.3 microduplication syndrome;Miller-Dieker syndrome.
== Function ==
[https://www.uniprot.org/uniprot/1433E_HUMAN 1433E_HUMAN] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Daumke O]]
[[Category: Roske Y]]
[[Category: Rrustemi T]]
[[Category: Selbach M]]
Retrieved from "https://proteopedia.org/8q1s"