3q0v: Difference between revisions
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<StructureSection load='3q0v' size='340' side='right'caption='[[3q0v]], [[Resolution|resolution]] 1.95Å' scene=''> | <StructureSection load='3q0v' size='340' side='right'caption='[[3q0v]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3q0v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3q0v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q0V FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LL4:4-METHYL-1-{4-[3-(THIOPHEN-2-YL)-1,2,4-OXADIAZOL-5-YL]PIPERIDIN-1-YL}PENTAN-1-ONE'>LL4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q0v OCA], [https://pdbe.org/3q0v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q0v RCSB], [https://www.ebi.ac.uk/pdbsum/3q0v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q0v ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q0v OCA], [https://pdbe.org/3q0v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q0v RCSB], [https://www.ebi.ac.uk/pdbsum/3q0v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q0v ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref> | |||
==See Also== | ==See Also== | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Baulard | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Brodin | [[Category: Baulard A]] | ||
[[Category: Carette | [[Category: Brodin P]] | ||
[[Category: Christophe | [[Category: Carette X]] | ||
[[Category: Demirkaya | [[Category: Christophe T]] | ||
[[Category: Deprez | [[Category: Demirkaya F]] | ||
[[Category: Desroses | [[Category: Deprez B]] | ||
[[Category: Dirie | [[Category: Desroses M]] | ||
[[Category: Flipo | [[Category: Dirie B]] | ||
[[Category: Jeon | [[Category: Flipo M]] | ||
[[Category: Lens | [[Category: Jeon HK]] | ||
[[Category: Leroux | [[Category: Lens Z]] | ||
[[Category: Locht | [[Category: Leroux F]] | ||
[[Category: Piveteau | [[Category: Locht C]] | ||
[[Category: Rucktooa | [[Category: Piveteau C]] | ||
[[Category: Villeret | [[Category: Rucktooa P]] | ||
[[Category: Willand | [[Category: Villeret V]] | ||
[[Category: Willand N]] | |||
Latest revision as of 10:45, 21 February 2024
ETHR From mycobacterium tuberculosis in complex with compound bdm31369
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