5qr2: Difference between revisions
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<StructureSection load='5qr2' size='340' side='right'caption='[[5qr2]], [[Resolution|resolution]] 1.66Å' scene=''> | <StructureSection load='5qr2' size='340' side='right'caption='[[5qr2]], [[Resolution|resolution]] 1.66Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5qr2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QR2 OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5qr2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QR2 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NTG:5-(1,4-oxazepan-4-yl)pyridine-2-carbonitrile'>NTG</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.66Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NTG:5-(1,4-oxazepan-4-yl)pyridine-2-carbonitrile'>NTG</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qr2 OCA], [https://pdbe.org/5qr2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qr2 RCSB], [https://www.ebi.ac.uk/pdbsum/5qr2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qr2 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
[ | [https://www.uniprot.org/uniprot/HEM0_HUMAN HEM0_HUMAN] X-linked sideroblastic anemia;Erythropoietic protoporphyria. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. Gain of function mutations in ALS2 are responsible for XLDPT, but they can also be a possible aggravating factor in congenital erythropoietic porphyria and other erythropoietic disorders caused by mutations in other genes (PubMed:21309041).<ref>PMID:21309041</ref> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/HEM0_HUMAN HEM0_HUMAN] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith CH]] | ||
[[Category: Bailey | [[Category: Bailey H]] | ||
[[Category: Bezerra | [[Category: Bezerra GA]] | ||
[[Category: Bountra | [[Category: Bountra C]] | ||
[[Category: Brandao-Neto | [[Category: Brandao-Neto J]] | ||
[[Category: Brennan | [[Category: Brennan PE]] | ||
[[Category: Douangamath A]] | |||
[[Category: Douangamath | [[Category: Edwards A]] | ||
[[Category: Edwards | [[Category: Foster W]] | ||
[[Category: Foster | [[Category: Krojer T]] | ||
[[Category: Krojer | [[Category: Nicola BB]] | ||
[[Category: Nicola | [[Category: Shrestha L]] | ||
[[Category: Shrestha | [[Category: Talon R]] | ||
[[Category: Talon | [[Category: Yue WW]] | ||
[[Category: Yue | [[Category: Von Delft F]] | ||
[[Category: | |||
Latest revision as of 11:25, 21 February 2024
PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z1348371854
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