5qyi: Difference between revisions

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==PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry G12a==

== Structural highlights ==

<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QYI OCA]. For a guided tour on the structure components use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5QYI FirstGlance].

<table><tr><td colspan='2'>[[5qyi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QYI OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=5QYI FirstGlance].

</td></tr><tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[~~http~~://proteopedia.org/fgij/fg.htm?mol=5qyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qyi OCA], [~~http~~://pdbe.org/5qyi PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5qyi RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5qyi PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5qyi ProSAT]</td></tr>

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.58Å</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGR:R-1,2-PROPANEDIOL'>PGR</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SZ7:~{N}-[(~{E})-thiophen-2-ylmethylideneamino]cyclopropanecarboxamide'>SZ7</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=5qyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qyi OCA], [https://pdbe.org/5qyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qyi RCSB], [https://www.ebi.ac.uk/pdbsum/5qyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qyi ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/PRP8_YEAST PRP8_YEAST] Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region. Also has a role in cell cycle.<ref>PMID:2835658</ref> <ref>PMID:9150140</ref> <ref>PMID:12773561</ref> <ref>PMID:18779563</ref>

==See Also==

*[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]]

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Saccharomyces cerevisiae S288C]]

[[Category: Barthel T]]

[[Category: Heine A]]

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@@ Line 1: / Line 1: @@
 ==PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry G12a==
-<StructureSection load='5qyi' size='340' side='right'caption='[[5qyi]]' scene=''>
+<StructureSection load='5qyi' size='340' side='right'caption='[[5qyi]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QYI OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5QYI FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5qyi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QYI FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5qyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qyi OCA], [http://pdbe.org/5qyi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qyi RCSB], [http://www.ebi.ac.uk/pdbsum/5qyi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qyi ProSAT]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.58&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGR:R-1,2-PROPANEDIOL'>PGR</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SZ7:~{N}-[(~{E})-thiophen-2-ylmethylideneamino]cyclopropanecarboxamide'>SZ7</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qyi OCA], [https://pdbe.org/5qyi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qyi RCSB], [https://www.ebi.ac.uk/pdbsum/5qyi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qyi ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/PRP8_YEAST PRP8_YEAST] Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region. Also has a role in cell cycle.<ref>PMID:2835658</ref> <ref>PMID:9150140</ref> <ref>PMID:12773561</ref> <ref>PMID:18779563</ref>
+==See Also==
+*[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]]
+== References ==
+<references/>
 __TOC__
 </StructureSection>
 [[Category: Large Structures]]
+[[Category: Saccharomyces cerevisiae S288C]]
 [[Category: Barthel T]]
 [[Category: Heine A]]