5r4g: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
<StructureSection load='5r4g' size='340' side='right'caption='[[5r4g]], [[Resolution|resolution]] 1.25Å' scene=''> | <StructureSection load='5r4g' size='340' side='right'caption='[[5r4g]], [[Resolution|resolution]] 1.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5r4g]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5R4G OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5r4g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5R4G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5R4G FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=RU4:4-(1,2,3-thiadiazol-4-yl)phenyl+ethylcarbamate'>RU4</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=RU4:4-(1,2,3-thiadiazol-4-yl)phenyl+ethylcarbamate'>RU4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5r4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5r4g OCA], [https://pdbe.org/5r4g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5r4g RCSB], [https://www.ebi.ac.uk/pdbsum/5r4g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5r4g ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/BPTF_HUMAN BPTF_HUMAN] Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Aimon | [[Category: Aimon A]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith CH]] | ||
[[Category: Bountra | [[Category: Bountra C]] | ||
[[Category: Bradley | [[Category: Bradley AR]] | ||
[[Category: Brandao-Neto | [[Category: Brandao-Neto J]] | ||
[[Category: Brennan | [[Category: Brennan PE]] | ||
[[Category: Collins | [[Category: Collins P]] | ||
[[Category: Dias A]] | |||
[[Category: Dias | [[Category: Douangamath A]] | ||
[[Category: Douangamath | [[Category: Edwards A]] | ||
[[Category: Edwards | [[Category: Fairhead M]] | ||
[[Category: Fairhead | [[Category: Krojer T]] | ||
[[Category: Krojer | [[Category: MacLean E]] | ||
[[Category: MacLean | [[Category: Renjie Z]] | ||
[[Category: Renjie | [[Category: Sethi R]] | ||
[[Category: Sethi | [[Category: Talon R]] | ||
[[Category: Talon | [[Category: Wright N]] | ||
[[Category: Wright | [[Category: Von Delft F]] | ||
[[Category: | |||
Revision as of 11:35, 21 February 2024
PanDDA analysis group deposition -- CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF in complex with FMOPL000621a
| ||||||||||||
