8p00: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Cryo-EM structure of Rotavirus B NSP2== | |||
<StructureSection load='8p00' size='340' side='right'caption='[[8p00]], [[Resolution|resolution]] 3.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8p00]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Rotavirus_B Rotavirus B]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8P00 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8P00 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8p00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8p00 OCA], [https://pdbe.org/8p00 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8p00 RCSB], [https://www.ebi.ac.uk/pdbsum/8p00 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8p00 ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Chamera | == Function == | ||
[https://www.uniprot.org/uniprot/Q6XD98_ROTGA Q6XD98_ROTGA] Participates in replication and packaging of the viral genome. Plays a crucial role, together with NSP5, in the formation of virus factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place. Displays ssRNA binding, NTPase, RNA triphosphatase (RTPase) and ATP-independent helix-unwinding activities. The unwinding activity may prepare and organize plus-strand RNAs for packaging and replication by removing interfering secondary structures. The RTPase activity plays a role in the removal of the gamma-phosphate from the rotavirus RNA minus strands of dsRNA genome segments.[HAMAP-Rule:MF_04089] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Rotavirus B]] | |||
[[Category: Chamera S]] | |||
[[Category: Nowotny M]] | |||
Latest revision as of 09:38, 1 March 2024
Cryo-EM structure of Rotavirus B NSP2
| ||||||||||||
