8aw2: Difference between revisions

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'''Unreleased structure'''


The entry 8aw2 is ON HOLD
==Mouse serotonin 5-HT3A receptor in complex with vortioxetine==
 
<StructureSection load='8aw2' size='340' side='right'caption='[[8aw2]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
Authors: Lopez-Sanchez, U., Nury, H.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8aw2]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8AW2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8AW2 FirstGlance]. <br>
Description: Mouse serotonin 5-HT3A receptor in complex with vortioxetine
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.01&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=VTX:Vortioxetine'>VTX</scene></td></tr>
[[Category: Lopez-Sanchez, U]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8aw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8aw2 OCA], [https://pdbe.org/8aw2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8aw2 RCSB], [https://www.ebi.ac.uk/pdbsum/8aw2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8aw2 ProSAT]</span></td></tr>
[[Category: Nury, H]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/5HT3A_MOUSE 5HT3A_MOUSE] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Lopez-Sanchez U]]
[[Category: Nury H]]
Retrieved from "https://proteopedia.org/8aw2"