8vlx: Difference between revisions

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'''Unreleased structure'''


The entry 8vlx is ON HOLD
==HTT in complex with HAP40 and a small molecule.==
 
<StructureSection load='8vlx' size='340' side='right'caption='[[8vlx]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
Authors: Poweleit, N., Boudet, J., Doherty, E.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8vlx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8VLX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8VLX FirstGlance]. <br>
Description: HTT in complex with HAP40 and a small molecule.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1ACS:N-[(1S,2R)-2-benzylcyclopentyl]-N-{1-[(1S)-1-(pyridin-4-yl)ethyl]piperidin-4-yl}urea'>A1ACS</scene></td></tr>
[[Category: Boudet, J]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8vlx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8vlx OCA], [https://pdbe.org/8vlx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8vlx RCSB], [https://www.ebi.ac.uk/pdbsum/8vlx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8vlx ProSAT]</span></td></tr>
[[Category: Doherty, E]]
</table>
[[Category: Poweleit, N]]
== Disease ==
[https://www.uniprot.org/uniprot/HD_HUMAN HD_HUMAN] Juvenile Huntington disease;Huntington disease. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/HD_HUMAN HD_HUMAN] May play a role in microtubule-mediated transport or vesicle function.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Boudet J]]
[[Category: Doherty E]]
[[Category: Poweleit N]]

Revision as of 12:11, 6 March 2024

HTT in complex with HAP40 and a small molecule.

8vlx, resolution 2.60Å

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