7k95: Difference between revisions

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====

==Crystal structure of human CPSF30 in complex with hFip1==

== Structural highlights ==

<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a guided tour on the structure components use [~~http~~://proteopedia.org/fgij/fg.htm?mol= FirstGlance].

<table><tr><td colspan='2'>[[7k95]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7K95 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=7K95 FirstGlance].

</td></tr><tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[~~http~~://proteopedia.org/fgij/fg.htm?mol=7k95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7k95 OCA], [~~http~~://pdbe.org/7k95 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=7k95 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/7k95 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=7k95 ProSAT]</td></tr>

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=7k95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7k95 OCA], [https://pdbe.org/7k95 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7k95 RCSB], [https://www.ebi.ac.uk/pdbsum/7k95 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7k95 ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/CPSF4_HUMAN CPSF4_HUMAN] Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).<ref>PMID:9224719</ref> <ref>PMID:14749727</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: ~~Z-disk~~]]

[[Category: Hamilton K]]

[[Category: Tong L]]

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-====
+==Crystal structure of human CPSF30 in complex with hFip1==
-<StructureSection load='7k95' size='340' side='right'caption='[[7k95]]' scene=''>
+<StructureSection load='7k95' size='340' side='right'caption='[[7k95]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
+<table><tr><td colspan='2'>[[7k95]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7K95 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7K95 FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7k95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7k95 OCA], [http://pdbe.org/7k95 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7k95 RCSB], [http://www.ebi.ac.uk/pdbsum/7k95 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7k95 ProSAT]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7k95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7k95 OCA], [https://pdbe.org/7k95 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7k95 RCSB], [https://www.ebi.ac.uk/pdbsum/7k95 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7k95 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/CPSF4_HUMAN CPSF4_HUMAN] Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).<ref>PMID:9224719</ref> <ref>PMID:14749727</ref>
+== References ==
+<references/>
 __TOC__
 </StructureSection>
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Z-disk]]
+[[Category: Hamilton K]]
+[[Category: Tong L]]