2zbt: Difference between revisions

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<StructureSection load='2zbt' size='340' side='right'caption='[[2zbt]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='2zbt' size='340' side='right'caption='[[2zbt]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2zbt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZBT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZBT FirstGlance]. <br>
<table><tr><td colspan='2'>[[2zbt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZBT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZBT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pdxS ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zbt OCA], [https://pdbe.org/2zbt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zbt RCSB], [https://www.ebi.ac.uk/pdbsum/2zbt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zbt ProSAT], [https://www.topsan.org/Proteins/RSGI/2zbt TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zbt OCA], [https://pdbe.org/2zbt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zbt RCSB], [https://www.ebi.ac.uk/pdbsum/2zbt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zbt ProSAT], [https://www.topsan.org/Proteins/RSGI/2zbt TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PDXS_THET8 PDXS_THET8] Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.[HAMAP-Rule:MF_01824]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Thet8]]
[[Category: Thermus thermophilus HB8]]
[[Category: Ebihara, A]]
[[Category: Ebihara A]]
[[Category: Fujimoto, Y]]
[[Category: Fujimoto Y]]
[[Category: Kuramitsu, S]]
[[Category: Kuramitsu S]]
[[Category: Manzoku, M]]
[[Category: Manzoku M]]
[[Category: Structural genomic]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S]]
[[Category: Lyase]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Pyridoxine biosynthesis]]
[[Category: Rsgi]]

Latest revision as of 13:56, 13 March 2024

Crystal structure of pyridoxine biosynthesis protein from Thermus thermophilus HB8

2zbt, resolution 1.65Å

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