3qbu: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
<StructureSection load='3qbu' size='340' side='right'caption='[[3qbu]], [[Resolution|resolution]] 2.57Å' scene=''> | <StructureSection load='3qbu' size='340' side='right'caption='[[3qbu]], [[Resolution|resolution]] 2.57Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3qbu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3qbu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_G27 Helicobacter pylori G27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QBU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QBU FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5701Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qbu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qbu OCA], [https://pdbe.org/3qbu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qbu RCSB], [https://www.ebi.ac.uk/pdbsum/3qbu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qbu ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qbu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qbu OCA], [https://pdbe.org/3qbu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qbu RCSB], [https://www.ebi.ac.uk/pdbsum/3qbu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qbu ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
= | [https://www.uniprot.org/uniprot/PGDAE_HELPG PGDAE_HELPG] Catalyzes the N-deacetylation of peptidoglycan (PG), an important mechanism that appears to confer lysozyme resistance and to mitigate host immune detection; this likely contributes to pathogen persistence in the host. The exact nature of the residue in PG that is deacetylated has not been determined. Is also able to catalyze the deacetylation of acetylated xylan, and, to a lesser extent, that of chitin and chitosan. Therefore, this enzyme might play a role during infection, considering that xylan-containing carbohydrate structures are among those commonly consumed by humans (By similarity). In vitro, does not show activity on N-acetylglucosamine (GlcNAc), chitotriose (GlcNAc3), some N-acetyl-dipeptides and allantoinase.<ref>PMID:21559431</ref> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Helicobacter pylori G27]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Cendron | [[Category: Cendron L]] | ||
[[Category: Percudani | [[Category: Percudani R]] | ||
[[Category: Shaik | [[Category: Shaik MM]] | ||
[[Category: Zanotti | [[Category: Zanotti G]] | ||
Latest revision as of 11:39, 14 March 2024
Crystal structure of putative peptidoglycan deactelyase (HP0310) from Helicobacter pylori
| ||||||||||||
