3twb: Difference between revisions

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<StructureSection load='3twb' size='340' side='right'caption='[[3twb]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
<StructureSection load='3twb' size='340' side='right'caption='[[3twb]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3twb]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Salep Salep]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TWB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TWB FirstGlance]. <br>
<table><tr><td colspan='2'>[[3twb]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Enteritidis_str._P125109 Salmonella enterica subsp. enterica serovar Enteritidis str. P125109]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TWB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TWB FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GCO:GLUCONIC+ACID'>GCO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3tw9|3tw9]], [[3twa|3twa]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GCO:GLUCONIC+ACID'>GCO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SEN1436 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=550537 SALEP])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3twb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3twb OCA], [https://pdbe.org/3twb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3twb RCSB], [https://www.ebi.ac.uk/pdbsum/3twb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3twb ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3twb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3twb OCA], [https://pdbe.org/3twb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3twb RCSB], [https://www.ebi.ac.uk/pdbsum/3twb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3twb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/DGD_SALEP DGD_SALEP]] Has low D-gluconate dehydratase activity (in vitro), suggesting that it has no significant role in D-gluconate degradation in vivo. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref>
[https://www.uniprot.org/uniprot/DGD_SALEP DGD_SALEP] Has low D-gluconate dehydratase activity (in vitro), suggesting that it has no significant role in D-gluconate degradation in vivo. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref>  
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Salep]]
[[Category: Salmonella enterica subsp. enterica serovar Enteritidis str. P125109]]
[[Category: Almo, S C]]
[[Category: Almo SC]]
[[Category: Bhosle, R]]
[[Category: Bhosle R]]
[[Category: Chowdhury, S]]
[[Category: Chowdhury S]]
[[Category: EFI, Enzyme Function Initiative]]
[[Category: Evans B]]
[[Category: Evans, B]]
[[Category: Gerlt JA]]
[[Category: Gerlt, J A]]
[[Category: Hammonds J]]
[[Category: Glenn, A Scott]]
[[Category: Hillerich B]]
[[Category: Hammonds, J]]
[[Category: Imker HJ]]
[[Category: Hillerich, B]]
[[Category: Patskovsky Y]]
[[Category: Imker, H J]]
[[Category: Scott Glenn A]]
[[Category: Patskovsky, Y]]
[[Category: Seidel RD]]
[[Category: Seidel, R D]]
[[Category: Toro R]]
[[Category: Toro, R]]
[[Category: Washington E]]
[[Category: Washington, E]]
[[Category: Zencheck WD]]
[[Category: Zencheck, W D]]
[[Category: Enolase]]
[[Category: Lyase]]
[[Category: Magnesium binding site]]
[[Category: Structural genomic]]

Latest revision as of 13:41, 14 March 2024

Crystal structure of gluconate dehydratase (TARGET EFI-501679) from Salmonella enterica subsp. enterica serovar Enteritidis str. P125109 complexed with magnesium and gluconic acid

3twb, resolution 1.76Å

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