7q2y: Difference between revisions
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==== | ==Cryo-EM structure of clamped S.cerevisiae condensin-DNA complex (form II)== | ||
<StructureSection load='7q2y' size='340' side='right'caption='[[7q2y]]' scene=''> | <StructureSection load='7q2y' size='340' side='right'caption='[[7q2y]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7q2y]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Q2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Q2Y FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7q2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7q2y OCA], [https://pdbe.org/7q2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7q2y RCSB], [https://www.ebi.ac.uk/pdbsum/7q2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7q2y ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7q2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7q2y OCA], [https://pdbe.org/7q2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7q2y RCSB], [https://www.ebi.ac.uk/pdbsum/7q2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7q2y ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/CND1_YEAST CND1_YEAST] Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. The condensin complex probably also plays a role during interphase.<ref>PMID:11854418</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Saccharomyces cerevisiae S288C]] | ||
[[Category: Synthetic construct]] | |||
[[Category: Lee B-G]] | |||
[[Category: Lowe J]] | |||
[[Category: Rhodes J]] | |||
Revision as of 16:04, 14 March 2024
Cryo-EM structure of clamped S.cerevisiae condensin-DNA complex (form II)
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