8p0v: Difference between revisions

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'''Unreleased structure'''


The entry 8p0v is ON HOLD  until Paper Publication
==Structure of the human Commander complex coiled coils, DENND10 and partial Retriever subcomplex==
 
<StructureSection load='8p0v' size='340' side='right'caption='[[8p0v]], [[Resolution|resolution]] 6.50&Aring;' scene=''>
Authors: Kumpula, E.P., Laulumaa, S., Huiskonen, J.T.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8p0v]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8P0V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8P0V FirstGlance]. <br>
Description: Structure of the human Commander complex coiled coils, DENND10 and partial Retriever subcomplex
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.5&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8p0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8p0v OCA], [https://pdbe.org/8p0v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8p0v RCSB], [https://www.ebi.ac.uk/pdbsum/8p0v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8p0v ProSAT]</span></td></tr>
[[Category: Kumpula, E.P]]
</table>
[[Category: Laulumaa, S]]
== Function ==
[[Category: Huiskonen, J.T]]
[https://www.uniprot.org/uniprot/VPS29_HUMAN VPS29_HUMAN] Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro).<ref>PMID:15247922</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Huiskonen JT]]
[[Category: Kumpula EP]]
[[Category: Laulumaa S]]

Revision as of 08:19, 20 March 2024

Structure of the human Commander complex coiled coils, DENND10 and partial Retriever subcomplex

8p0v, resolution 6.50Å

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