8wot: Difference between revisions
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==Cryo-EM structure of human SIDT1 protein with C2 symmetry at low pH== | |||
<StructureSection load='8wot' size='340' side='right'caption='[[8wot]], [[Resolution|resolution]] 3.18Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8wot]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8WOT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8WOT FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.18Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8wot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8wot OCA], [https://pdbe.org/8wot PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8wot RCSB], [https://www.ebi.ac.uk/pdbsum/8wot PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8wot ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/SIDT1_HUMAN SIDT1_HUMAN] In vitro binds long double-stranded RNA (dsRNA) (500 and 700 base pairs), but not dsRNA shorter than 300 bp. Not involved in RNA autophagy, a process in which RNA is directly imported into lysosomes in an ATP-dependent manner, and degraded.[UniProtKB:Q6AXF6] | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Liu W]] | |||
[[Category: Ru H]] | |||
[[Category: Tang M]] | |||
[[Category: Wang J]] | |||
[[Category: Wu S]] | |||
[[Category: Zhang X]] | |||
Latest revision as of 08:22, 20 March 2024
Cryo-EM structure of human SIDT1 protein with C2 symmetry at low pH
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