6if0: Difference between revisions
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==Crystal structure of CERT START domain in complex with compound D16== | ==Crystal structure of CERT START domain in complex with compound D16== | ||
<StructureSection load='6if0' size='340' side='right' | <StructureSection load='6if0' size='340' side='right'caption='[[6if0]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6if0]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[6if0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IF0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IF0 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A59:2-({4-pentyl-3-[(Z)-2-(pyridin-2-yl)ethenyl][1,1-biphenyl]-4-yl}sulfonyl)ethan-1-ol'>A59</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6if0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6if0 OCA], [https://pdbe.org/6if0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6if0 RCSB], [https://www.ebi.ac.uk/pdbsum/6if0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6if0 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Disease == | |||
[https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] The disease is caused by variants affecting the gene represented in this entry. | |||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.<ref>PMID:14685229</ref> <ref>PMID:17591919</ref> <ref>PMID:18184806</ref> <ref>PMID:20036255</ref> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Egawa | [[Category: Large Structures]] | ||
[[Category: Hanada | [[Category: Egawa D]] | ||
[[Category: Hanzawa | [[Category: Hanada K]] | ||
[[Category: Kawasaki | [[Category: Hanzawa H]] | ||
[[Category: Kobayashi | [[Category: Kawasaki S]] | ||
[[Category: Kumagai | [[Category: Kobayashi S]] | ||
[[Category: Nakao | [[Category: Kumagai K]] | ||
[[Category: Sakai | [[Category: Nakao N]] | ||
[[Category: Suzuki | [[Category: Sakai S]] | ||
[[Category: Ueno | [[Category: Suzuki M]] | ||
[[Category: Ueno M]] | |||
Latest revision as of 10:32, 27 March 2024
Crystal structure of CERT START domain in complex with compound D16
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