8jfk: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

The entry ~~8jfk is ON HOLD until Paper Publication~~

==PhK holoenzyme in inactive state, muscle isoform==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[8jfk]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JFK OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=8JFK FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAR:FARNESYL'>FAR</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=8jfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jfk OCA], [https://pdbe.org/8jfk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jfk RCSB], [https://www.ebi.ac.uk/pdbsum/8jfk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jfk ProSAT]</td></tr>

</table>

== Disease ==

[https://www.uniprot.org/uniprot/KPBB_HUMAN KPBB_HUMAN] Glycogen storage disease due to liver and muscle phosphorylase kinase deficiency. The disease is caused by variants affecting the gene represented in this entry.

== Function ==

[https://www.uniprot.org/uniprot/KPBB_HUMAN KPBB_HUMAN] Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Xiao JY]]

[[Category: Yang XK]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8jfk is ON HOLD  until Paper Publication
+==PhK holoenzyme in inactive state, muscle isoform==
+<StructureSection load='8jfk' size='340' side='right'caption='[[8jfk]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8jfk]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JFK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JFK FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAR:FARNESYL'>FAR</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jfk OCA], [https://pdbe.org/8jfk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jfk RCSB], [https://www.ebi.ac.uk/pdbsum/8jfk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jfk ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[https://www.uniprot.org/uniprot/KPBB_HUMAN KPBB_HUMAN] Glycogen storage disease due to liver and muscle phosphorylase kinase deficiency. The disease is caused by variants affecting the gene represented in this entry.
+== Function ==
+[https://www.uniprot.org/uniprot/KPBB_HUMAN KPBB_HUMAN] Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Xiao JY]]
+[[Category: Yang XK]]