8wfj: Difference between revisions

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'''Unreleased structure'''


The entry 8wfj is ON HOLD  until Paper Publication
==human glycine transporter 1 in complex with ALX-5407 in inward facing conformation==
 
<StructureSection load='8wfj' size='340' side='right'caption='[[8wfj]], [[Resolution|resolution]] 3.35&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8wfj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8WFJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8WFJ FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.35&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=W5F:ALX5407'>W5F</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8wfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8wfj OCA], [https://pdbe.org/8wfj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8wfj RCSB], [https://www.ebi.ac.uk/pdbsum/8wfj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8wfj ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/SC6A9_HUMAN SC6A9_HUMAN] Atypical glycine encephalopathy;Infantile glycine encephalopathy. The disease is caused by variants affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/SC6A9_HUMAN SC6A9_HUMAN] Sodium- and chloride-dependent glycine transporter (PubMed:8183239). Essential for regulating glycine concentrations at inhibitory glycinergic synapses.[UniProtKB:P28571]<ref>PMID:8183239</ref>  Sodium- and chloride-dependent glycine transporter.<ref>PMID:8183239</ref>  Sodium- and chloride-dependent glycine transporter.<ref>PMID:8183239</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Wei Y]]
[[Category: Zhao Y]]
Retrieved from "https://proteopedia.org/8wfj"