8wfl: Difference between revisions
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The entry | ==human glycine transporter 1 in complex with PF-03463275 in outward facing conformation== | ||
<StructureSection load='8wfl' size='340' side='right'caption='[[8wfl]], [[Resolution|resolution]] 3.03Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8wfl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8WFL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8WFL FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.03Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=W5X:PF-3463275'>W5X</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8wfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8wfl OCA], [https://pdbe.org/8wfl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8wfl RCSB], [https://www.ebi.ac.uk/pdbsum/8wfl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8wfl ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/SC6A9_HUMAN SC6A9_HUMAN] Atypical glycine encephalopathy;Infantile glycine encephalopathy. The disease is caused by variants affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SC6A9_HUMAN SC6A9_HUMAN] Sodium- and chloride-dependent glycine transporter (PubMed:8183239). Essential for regulating glycine concentrations at inhibitory glycinergic synapses.[UniProtKB:P28571]<ref>PMID:8183239</ref> Sodium- and chloride-dependent glycine transporter.<ref>PMID:8183239</ref> Sodium- and chloride-dependent glycine transporter.<ref>PMID:8183239</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Wei Y]] | |||
[[Category: Zhao Y]] | |||
Revision as of 05:52, 3 April 2024
human glycine transporter 1 in complex with PF-03463275 in outward facing conformation
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