6o24: Difference between revisions
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==== | ==Crystal structure of 4498 Fab in complex with circumsporozoite protein NANP3 and anti-Kappa VHH domain== | ||
<StructureSection load='6o24' size='340' side='right'caption='[[6o24]]' scene=''> | <StructureSection load='6o24' size='340' side='right'caption='[[6o24]], [[Resolution|resolution]] 1.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[6o24]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6O24 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6O24 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6o24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o24 OCA], [https://pdbe.org/6o24 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6o24 RCSB], [https://www.ebi.ac.uk/pdbsum/6o24 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6o24 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6o24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o24 OCA], [https://pdbe.org/6o24 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6o24 RCSB], [https://www.ebi.ac.uk/pdbsum/6o24 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6o24 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/CSP_PLAFO CSP_PLAFO] The circumsporozoite protein is the immunodominant surface antigen on the sporozoite (the infective stage of the malaria parasite that is transmitted from the mosquito to the vertebrate host). | |||
==See Also== | |||
*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Lama glama]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Plasmodium falciparum]] | ||
[[Category: Bosch A]] | |||
[[Category: Julien JP]] | |||
[[Category: Murugan R]] | |||
[[Category: Prieto K]] | |||
[[Category: Scally SW]] | |||
[[Category: Wardemann H]] | |||
