8rcw: Difference between revisions
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==Crystal structure of the Mycobacterium tuberculosis regulator VirS (N-terminal fragment 4-208) in complex with the lead compound SMARt751== | |||
<StructureSection load='8rcw' size='340' side='right'caption='[[8rcw]], [[Resolution|resolution]] 1.69Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8rcw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8RCW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8RCW FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.692Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=YQF:4,4,4-tris(fluoranyl)-1-[4-(4-fluorophenyl)piperidin-1-yl]butan-1-one'>YQF</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8rcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8rcw OCA], [https://pdbe.org/8rcw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8rcw RCSB], [https://www.ebi.ac.uk/pdbsum/8rcw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8rcw ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Grosse | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/VIRS_MYCTU VIRS_MYCTU] Regulates the expression of the mymA operon (Rv3083-Rv3089).<ref>PMID:14568148</ref> | ||
[[Category: | == References == | ||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis H37Rv]] | |||
[[Category: Baulard AR]] | |||
[[Category: Grosse C]] | |||
[[Category: Megalizzi V]] | |||
[[Category: Sigoillot M]] | |||
[[Category: Tanina A]] | |||
[[Category: Willand N]] | |||
[[Category: Wintjens R]] | |||