8tm2: Difference between revisions

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'''Unreleased structure'''


The entry 8tm2 is ON HOLD  until Paper Publication
==Preclinical Characterization of Pan-NKG2D Ligand-Binding NKG2D Receptor Decoys==
 
<StructureSection load='8tm2' size='340' side='right'caption='[[8tm2]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
Authors: Rupert, P.B., Strong, R.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8tm2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TM2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TM2 FirstGlance]. <br>
Description: Preclinical Characterization of Pan-NKG2D Ligand-Binding NKG2D Receptor Decoys
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
[[Category: Strong, R]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tm2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tm2 OCA], [https://pdbe.org/8tm2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tm2 RCSB], [https://www.ebi.ac.uk/pdbsum/8tm2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tm2 ProSAT]</span></td></tr>
[[Category: Rupert, P.B]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/NKG2D_HUMAN NKG2D_HUMAN] Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Rupert PB]]
[[Category: Strong R]]
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