Sandbox Ben Whiteside: Difference between revisions
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=== Bypass Motif === | === Bypass Motif === | ||
=== G-alpha Interactions with CTR TMD === | === G-alpha Interactions with CTR TMD === | ||
To transduce the signal across the cell membrane, the binding of amylin will induce a conformational change that allows for the CTR to make favorable interactions with the G alpha subunit. Two interactions shown <scene name='10/1038828/Ctr_g_alpha/15'>here </scene> | To transduce the signal across the cell membrane, the binding of amylin will induce a conformational change that allows for the CTR to make favorable interactions with the G alpha subunit. Two interactions shown <scene name='10/1038828/Ctr_g_alpha/15'>here </scene><scene name='10/1038828/Ctr_g_alpha/12'>here </scene> activate the G-protein and propel downstream signaling. | ||