User:Brynn Baker/Sandbox1: Difference between revisions
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[[Image:Amylin_alignment_sequence.png|400 px|left|thumb|Figure 2. Amylin sequence alignment for human amylin, rat amylin, and pramlintide. Green represents fully conserved residues, pink represents positive to positive, red is nonpolar to nonpolar, and black is polar to nonpolar.]] | [[Image:Amylin_alignment_sequence.png|400 px|left|thumb|Figure 2. Amylin sequence alignment for human amylin, rat amylin, and pramlintide. Green represents fully conserved residues, pink represents positive to positive, red is nonpolar to nonpolar, and black is polar to nonpolar.]] | ||
== Amylin Receptor == | == Amylin Receptor == | ||
The amylin receptor (AMYR) is the result of the heterodimerization of the <scene name='10/1037516/Ct/2'>calcitonin receptor</scene> and a RAMP, such as <scene name='10/1037516/Ramp3/2'>RAMP3</scene>. The patterns of peptide interaction between CT and AMYR are very similar overall, but amylin has a higher affinity for AMYR1 and AMYR3 than AMYR2<ref name="Cao">PMID:35324283</ref>. | The amylin receptor (AMYR) is the result of the heterodimerization of the <scene name='10/1037516/Ct/2'>calcitonin receptor</scene> and a RAMP, such as <scene name='10/1037516/Ramp3/2'>RAMP3</scene>. The patterns of peptide interaction between CT and AMYR are very similar overall, but amylin has a higher affinity for AMYR1 and AMYR3 than AMYR2<ref name="Cao">PMID:35324283</ref>. | ||
