Sandbox 323: Difference between revisions

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The beginning experiments were conducted on molecular docking sites to compare the structure of the 3DS8 active site with known proteins. Using the SPRITE database [2], the 3DS8 protein was matched with a few proteases through right-handed superpositions with RMSD values ranging from 1.20-1.40, indicating relative similarities.
The beginning experiments were conducted on molecular docking sites to compare the structure of the 3DS8 active site with known proteins. Using the SPRITE database [2], the 3DS8 protein was matched with a few proteases through right-handed superpositions with RMSD values ranging from 1.20-1.40, indicating relative similarities.
The left-handed superpositions matched with more trypsins and displayed better RMSD values ranging from 0.93-1.11.
The left-handed superpositions matched with more trypsins and displayed better RMSD values ranging from 0.93-1.11.
[[Image:Screenshot 2024-04-28 at 5.35.14 PM.png]]


The 3DS8 protein did not have many very specific active site matches with known proteins on the Chimera software [3], however, it was very similar to trypsin,
The 3DS8 protein did not have many very specific active site matches with known proteins on the Chimera software [3], however, it was very similar to trypsin,