8h6e: Difference between revisions
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==Cryo-EM structure of human exon-defined spliceosome in the late pre-B state.== | |||
<StructureSection load='8h6e' size='340' side='right'caption='[[8h6e]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8h6e]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8H6E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8H6E FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=IHP:INOSITOL+HEXAKISPHOSPHATE'>IHP</scene>, <scene name='pdbligand=M7M:N,N,7-TRIMETHYLGUANOSINE+5-(TRIHYDROGEN+DIPHOSPHATE)'>M7M</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8h6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8h6e OCA], [https://pdbe.org/8h6e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8h6e RCSB], [https://www.ebi.ac.uk/pdbsum/8h6e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8h6e ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/LSM2_HUMAN LSM2_HUMAN] Binds specifically to the 3'-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Bai R]] | |||
[[Category: Lei J]] | |||
[[Category: Shi Y]] | |||
[[Category: Yan C]] | |||
[[Category: Zhan X]] | |||
[[Category: Zhang W]] | |||
[[Category: Zhang X]] | |||
Revision as of 06:18, 1 May 2024
Cryo-EM structure of human exon-defined spliceosome in the late pre-B state.
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