8ouj: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 8ouj is ~~ON HOLD until Paper Publication~~

==Heterotrimeric Complex of Human ASCT2 with Syncytin-1==

~~Authors~~: ~~Khare~~, S., ~~Reyes~~, N.

== Structural highlights ==

<table><tr><td colspan='2'>[[8ouj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8OUJ OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=8OUJ FirstGlance].

~~Description~~: ~~Heterotrimeric Complex~~ of ~~Human ASCT2 with Syncytin~~-1

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5Å</td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene></td></tr>

[[Category: ~~Reyes, N~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=8ouj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ouj OCA], [https://pdbe.org/8ouj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ouj RCSB], [https://www.ebi.ac.uk/pdbsum/8ouj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ouj ProSAT]</td></tr>

[[Category: Khare, S]]

</table>

== Function ==

[https://www.uniprot.org/uniprot/AAAT_HUMAN AAAT_HUMAN] Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids (PubMed:8702519). Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904).<ref>PMID:10708449</ref> <ref>PMID:23492904</ref> <ref>PMID:8702519</ref> (Microbial infection) Acts as a cell surface receptor for Feline endogenous virus RD114.<ref>PMID:10051606</ref> <ref>PMID:10196349</ref> (Microbial infection) Acts as a cell surface receptor for Baboon M7 endogenous virus.<ref>PMID:10196349</ref> (Microbial infection) Acts as a cell surface receptor for type D simian retroviruses.<ref>PMID:10196349</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Khare S]]

[[Category: Reyes N]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8ouj is ON HOLD  until Paper Publication
+==Heterotrimeric Complex of Human ASCT2 with Syncytin-1==
+<StructureSection load='8ouj' size='340' side='right'caption='[[8ouj]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
-Authors: Khare, S., Reyes, N.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8ouj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8OUJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8OUJ FirstGlance]. <br>
-Description: Heterotrimeric Complex of Human ASCT2 with Syncytin-1
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene></td></tr>
-[[Category: Reyes, N]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ouj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ouj OCA], [https://pdbe.org/8ouj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ouj RCSB], [https://www.ebi.ac.uk/pdbsum/8ouj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ouj ProSAT]</span></td></tr>
-[[Category: Khare, S]]
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/AAAT_HUMAN AAAT_HUMAN] Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids (PubMed:8702519). Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904).<ref>PMID:10708449</ref> <ref>PMID:23492904</ref> <ref>PMID:8702519</ref>   (Microbial infection) Acts as a cell surface receptor for Feline endogenous virus RD114.<ref>PMID:10051606</ref> <ref>PMID:10196349</ref>   (Microbial infection) Acts as a cell surface receptor for Baboon M7 endogenous virus.<ref>PMID:10196349</ref>   (Microbial infection) Acts as a cell surface receptor for type D simian retroviruses.<ref>PMID:10196349</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Khare S]]
+[[Category: Reyes N]]