9ey8: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry 9ey8 is ON HOLD~~

==Crystal structure of human tyrosinase-related protein 1 (TYRP1) in complex with (s)-amino-L-tyrosine==

~~Authors: Ng, Y.M., Soler-Lopez, M.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[9ey8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9EY8 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=9EY8 FirstGlance].

~~Description:~~ Crystal structure of human tyrosinase-related protein 1 (TYRP1) in complex with (s)-amino-L-tyrosine

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TY2:3-AMINO-L-TYROSINE'>TY2</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

[[Category: ~~Soler-Lopez, M~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=9ey8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ey8 OCA], [https://pdbe.org/9ey8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ey8 RCSB], [https://www.ebi.ac.uk/pdbsum/9ey8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ey8 ProSAT]</td></tr>

[[Category: ~~Ng, Y.~~M]]

</table>

== Disease ==

[https://www.uniprot.org/uniprot/TYRP1_HUMAN TYRP1_HUMAN] Oculocutaneous albinism type 3. The disease is caused by mutations affecting the gene represented in this entry.

== Function ==

[https://www.uniprot.org/uniprot/TYRP1_HUMAN TYRP1_HUMAN] Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin.[UniProtKB:P07147]

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Ng YM]]

[[Category: Soler-Lopez M]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 9ey8 is ON HOLD
+==Crystal structure of human tyrosinase-related protein 1 (TYRP1) in complex with (s)-amino-L-tyrosine==
+<StructureSection load='9ey8' size='340' side='right'caption='[[9ey8]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-Authors: Ng, Y.M., Soler-Lopez, M.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[9ey8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9EY8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9EY8 FirstGlance]. <br>
-Description: Crystal structure of human tyrosinase-related protein 1 (TYRP1) in complex with (s)-amino-L-tyrosine
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TY2:3-AMINO-L-TYROSINE'>TY2</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Soler-Lopez, M]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ey8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ey8 OCA], [https://pdbe.org/9ey8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ey8 RCSB], [https://www.ebi.ac.uk/pdbsum/9ey8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ey8 ProSAT]</span></td></tr>
-[[Category: Ng, Y.M]]
+</table>
+== Disease ==
+[https://www.uniprot.org/uniprot/TYRP1_HUMAN TYRP1_HUMAN] Oculocutaneous albinism type 3. The disease is caused by mutations affecting the gene represented in this entry.
+== Function ==
+[https://www.uniprot.org/uniprot/TYRP1_HUMAN TYRP1_HUMAN] Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin.[UniProtKB:P07147]
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Ng YM]]
+[[Category: Soler-Lopez M]]