2kka: Difference between revisions

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kka FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kka OCA], [https://pdbe.org/2kka PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kka RCSB], [https://www.ebi.ac.uk/pdbsum/2kka PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kka ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kka FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kka OCA], [https://pdbe.org/2kka PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kka RCSB], [https://www.ebi.ac.uk/pdbsum/2kka PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kka ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Human telomeric DNA G-quadruplex has been considered as an attractive target for cancer therapeutic intervention. The telomeric sequence shows intrinsic structure polymorphism. Here we report a novel intramolecular G-quadruplex structure formed by a variant human telomeric sequence in K(+) solution. This sequence forms a basket-type intramolecular G-quadruplex with only two G-tetrads but multiple-layer capping structures formed by loop residues. While it is shown that this structure can only be detected in the specifically truncated telomeric sequences without any 5'-flanking residues, our results suggest that this two-G-tetrad conformation is likely to be an intermediate form of the interconversion of different telomeric G-quadruplex conformations.
Structure of a two-G-tetrad intramolecular G-quadruplex formed by a variant human telomeric sequence in K+ solution: insights into the interconversion of human telomeric G-quadruplex structures.,Zhang Z, Dai J, Veliath E, Jones RA, Yang D Nucleic Acids Res. 2010 Jan;38(3):1009-21. Epub 2009 Nov 27. PMID:19946019<ref>PMID:19946019</ref>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 2kka" style="background-color:#fffaf0;"></div>
== References ==
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