2mdu: Difference between revisions

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mdu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdu OCA], [https://pdbe.org/2mdu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mdu RCSB], [https://www.ebi.ac.uk/pdbsum/2mdu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mdu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mdu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdu OCA], [https://pdbe.org/2mdu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mdu RCSB], [https://www.ebi.ac.uk/pdbsum/2mdu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mdu ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
A hyperstable Pin1 WW domain has been circularly permuted via excision of the fold-nucleating turn; it still folds to form the native three-strand sheet and hydrophobic core features. Multiprobe folding dynamics studies of the normal and circularly permuted sequences, as well as their constituent hairpin fragments and comparable-length beta-strand-loop-beta-strand models, indicate 2-state folding for all topologies. N-terminal hairpin formation is the fold nucleating event for the wild-type sequence; the slower folding circular permutant has a more distributed folding transition state.
Circular Permutation of a WW Domain: Folding Still Occurs after Excising the Turn of the Folding-Nucleating Hairpin.,Kier BL, Anderson JM, Andersen NH J Am Chem Soc. 2014 Jan 3. PMID:24350581<ref>PMID:24350581</ref>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 2mdu" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Kier BL]]
[[Category: Kier BL]]
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