4bk8: Difference between revisions

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<StructureSection load='4bk8' size='340' side='right'caption='[[4bk8]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='4bk8' size='340' side='right'caption='[[4bk8]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4bk8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dsm_18386 Dsm 18386]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BK8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BK8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4bk8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ignicoccus_hospitalis Ignicoccus hospitalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BK8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BK8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.847&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bk8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bk8 OCA], [https://pdbe.org/4bk8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bk8 RCSB], [https://www.ebi.ac.uk/pdbsum/4bk8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bk8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bk8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bk8 OCA], [https://pdbe.org/4bk8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bk8 RCSB], [https://www.ebi.ac.uk/pdbsum/4bk8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bk8 ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
== Function ==
== Publication Abstract from PubMed ==
[https://www.uniprot.org/uniprot/A8AC72_IGNH4 A8AC72_IGNH4]
Superoxide reductases (SORs) are metalloproteins which constitute the most recently identified oxygen-detoxification system in anaerobic and microaerobic bacteria and archaea. SORs are involved in scavenging superoxide radicals from the cell by catalyzing the reduction of superoxide ({\rm O}_{2};{\bullet -}) to hydrogen peroxide and are characterized by a catalytic nonhaem iron centre coordinated by four histidine ligands and one cysteine ligand. Ignicoccus hospitalis, a hyperthermophilic crenarchaeon, is known to have a neelaredoxin-type SOR that keeps toxic oxygen species levels under control. Blue crystals of recombinant I. hospitalis oxidized neelaredoxin (14.1 kDa, 124 residues) were obtained. These crystals diffracted to 2.4 A resolution in-house at room temperature and belonged to the hexagonal space group P6(2)22 or P6(4)22, with unit-cell parameters a = b = 108, c = 64 A. Cell-content analysis indicated the presence of one monomer in the asymmetric unit.
 
Cloning, purification, crystallization and X-ray crystallographic analysis of Ignicoccus hospitalis neelaredoxin.,Pinho FG, Romao CV, Pinto AF, Saraiva LM, Huber H, Matias PM, Teixeira M, Bandeiras TM Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 May 1;66(Pt 5):605-7. doi:, 10.1107/S1744309110012030. Epub 2010 Apr 30. PMID:20445270<ref>PMID:20445270</ref>
 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 4bk8" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Dsm 18386]]
[[Category: Ignicoccus hospitalis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bandeiras, T M]]
[[Category: Bandeiras TM]]
[[Category: Barradas, A R]]
[[Category: Barradas AR]]
[[Category: Matias, P M]]
[[Category: Matias PM]]
[[Category: Pinho, F G]]
[[Category: Pinho FG]]
[[Category: Pinto, A F]]
[[Category: Pinto AF]]
[[Category: Romao, C V]]
[[Category: Romao CV]]
[[Category: Sousa, C M]]
[[Category: Sousa CM]]
[[Category: Teixeira, M]]
[[Category: Teixeira M]]
[[Category: Neelaredoxin]]
[[Category: Oxidative stress]]
[[Category: Oxidoreductase]]
[[Category: Symbiosis]]