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<StructureSection load='6hrn' size='340' side='right'caption='[[6hrn]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
<StructureSection load='6hrn' size='340' side='right'caption='[[6hrn]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6hrn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Nostoc_sp. Nostoc sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HRN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HRN FirstGlance]. <br>
<table><tr><td colspan='2'>[[6hrn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Nostoc_sp. Nostoc sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HRN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6HRN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYC:PHYCOCYANOBILIN'>CYC</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.513&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MEN:N-METHYL+ASPARAGINE'>MEN</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CYC:PHYCOCYANOBILIN'>CYC</scene>, <scene name='pdbligand=MEN:N-METHYL+ASPARAGINE'>MEN</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hrn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hrn OCA], [http://pdbe.org/6hrn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hrn RCSB], [http://www.ebi.ac.uk/pdbsum/6hrn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hrn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6hrn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hrn OCA], [https://pdbe.org/6hrn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6hrn RCSB], [https://www.ebi.ac.uk/pdbsum/6hrn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6hrn ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
== Function ==
== Publication Abstract from PubMed ==
[https://www.uniprot.org/uniprot/A0A509GUZ8_9NOSO A0A509GUZ8_9NOSO] Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex (phycobilisome, PBS). Phycocyanin is the major phycobiliprotein in the PBS rod.[ARBA:ARBA00003579]
Phycocyanin (PC) is the principal pigment protein in the light-harvesting antenna of cyanobacteria. Here the biochemical characterization and the 1.51A crystal structure of PC from cyanobacterium Nostoc sp. WR13 (Nst-PC) is reported. The P63 crystal lattice is composed of the minimal biological entities of Nst-PC, the (alphabeta)3 trimeric rings. The structure has been refined to R factor 11.5% (Rfree 15.4%) using anisotropic atomic B factors. A phylogenetic study shows that the alpha and beta chains of Nst-PC are significantly clustered in a distinct clade with Acaryochloris marina. The structure was examined to look for any significant differences between Nst-PC and PC from non-desert species. Only minor differences were found in the chromophore microenvironments. The tentative energy transfer pathways in Nst-PC were modeled based on simple structural considerations.


Crystal structure of phycocyanin from heterocyst-forming filamentous cyanobacterium Nostoc sp. WR13.,Patel HM, Roszak AW, Madamwar D, Cogdell RJ Int J Biol Macromol. 2019 May 20;135:62-68. doi: 10.1016/j.ijbiomac.2019.05.099. PMID:31121226<ref>PMID:31121226</ref>
==See Also==
 
*[[Phycocyanin|Phycocyanin]]
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 6hrn" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Nostoc sp]]
[[Category: Nostoc sp]]
[[Category: Cogdell, R J]]
[[Category: Cogdell RJ]]
[[Category: Madamwar, D]]
[[Category: Madamwar D]]
[[Category: Patel, H M]]
[[Category: Patel HM]]
[[Category: Roszak, A W]]
[[Category: Roszak AW]]
[[Category: Cyc chromophore]]
[[Category: Heterocyst forming filamentous cyanobacterium]]
[[Category: Photosynthesis]]
[[Category: Phycobilisome]]
[[Category: Phycocyanin]]

Latest revision as of 07:34, 1 May 2024

C-Phycocyanin from heterocyst forming filamentous cyanobacterium Nostoc sp. WR13

6hrn, resolution 1.51Å

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