8v24: Difference between revisions
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==LapB cytoplasmic domain in complex with LpxC== | |||
<StructureSection load='8v24' size='340' side='right'caption='[[8v24]], [[Resolution|resolution]] 3.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8v24]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_CFT073 Escherichia coli CFT073]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8V24 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8V24 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=24G:URIDINE-5-DIPHOSPHATE-3-O-(R-3-HYDROXYMYRISTOYL)-GLUCOSAMINE'>24G</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8v24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8v24 OCA], [https://pdbe.org/8v24 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8v24 RCSB], [https://www.ebi.ac.uk/pdbsum/8v24 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8v24 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/LAPB_ECOL6 LAPB_ECOL6] Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli CFT073]] | |||
[[Category: Large Structures]] | |||
[[Category: Mi W]] | |||
[[Category: Shu S]] | |||
Latest revision as of 08:05, 1 May 2024
LapB cytoplasmic domain in complex with LpxC
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