8yx9: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "8yx9" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
==CD40 in complex with Dacetuzumab Fab== | |||
<StructureSection load='8yx9' size='340' side='right'caption='[[8yx9]], [[Resolution|resolution]] 2.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8yx9]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8YX9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8YX9 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8yx9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8yx9 OCA], [https://pdbe.org/8yx9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8yx9 RCSB], [https://www.ebi.ac.uk/pdbsum/8yx9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8yx9 ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/TNR5_HUMAN TNR5_HUMAN] Defects in CD40 are the cause of immunodeficiency with hyper-IgM type 3 (HIGM3) [MIM:[https://omim.org/entry/606843 606843]. A rare immunodeficiency syndrome characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE. It results in a profound susceptibility to bacterial infections.<ref>PMID:11675497</ref> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TNR5_HUMAN TNR5_HUMAN] Receptor for TNFSF5/CD40LG. | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Caaveiro JMM]] | |||
[[Category: Fernandez-Perez J]] | |||
[[Category: Tsumoto K]] | |||
Revision as of 08:41, 9 May 2024
CD40 in complex with Dacetuzumab Fab
| ||||||||||||
