2jfd: Difference between revisions

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<StructureSection load='2jfd' size='340' side='right'caption='[[2jfd]], [[Resolution|resolution]] 2.81&Aring;' scene=''>
<StructureSection load='2jfd' size='340' side='right'caption='[[2jfd]], [[Resolution|resolution]] 2.81&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2jfd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JFD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JFD FirstGlance]. <br>
<table><tr><td colspan='2'>[[2jfd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JFD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JFD FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1xkt|1xkt]], [[2cg5|2cg5]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.81&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Fatty-acid_synthase Fatty-acid synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.85 2.3.1.85] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jfd OCA], [https://pdbe.org/2jfd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jfd RCSB], [https://www.ebi.ac.uk/pdbsum/2jfd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jfd ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jfd OCA], [https://pdbe.org/2jfd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jfd RCSB], [https://www.ebi.ac.uk/pdbsum/2jfd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jfd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/FAS_HUMAN FAS_HUMAN]] Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.  
[https://www.uniprot.org/uniprot/FAS_HUMAN FAS_HUMAN] Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Fatty-acid synthase]]
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H]]
[[Category: Arrowsmith CH]]
[[Category: Bunkoczi, G]]
[[Category: Bunkoczi G]]
[[Category: Edwards, A]]
[[Category: Edwards A]]
[[Category: Hozjan, V]]
[[Category: Hozjan V]]
[[Category: Kavanagh, K]]
[[Category: Kavanagh K]]
[[Category: Oppermann, U]]
[[Category: Oppermann U]]
[[Category: Rojkova, A]]
[[Category: Rojkova A]]
[[Category: Smith, S]]
[[Category: Smith S]]
[[Category: Sundstrom, M]]
[[Category: Sundstrom M]]
[[Category: Weigelt, J]]
[[Category: Weigelt J]]
[[Category: Wu, X]]
[[Category: Wu X]]
[[Category: Fatty acid biosynthesis]]
[[Category: Lipid synthesis]]
[[Category: Oxidoreductase]]
[[Category: Transferase]]