2wb8: Difference between revisions
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<StructureSection load='2wb8' size='340' side='right'caption='[[2wb8]], [[Resolution|resolution]] 2.15Å' scene=''> | <StructureSection load='2wb8' size='340' side='right'caption='[[2wb8]], [[Resolution|resolution]] 2.15Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2wb8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2wb8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WB8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WB8 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wb8 OCA], [https://pdbe.org/2wb8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wb8 RCSB], [https://www.ebi.ac.uk/pdbsum/2wb8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wb8 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wb8 OCA], [https://pdbe.org/2wb8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wb8 RCSB], [https://www.ebi.ac.uk/pdbsum/2wb8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wb8 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/HASP_HUMAN HASP_HUMAN] Serine/threonine-protein kinase that phosphorylates histone H3 at 'Ser-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.<ref>PMID:11228240</ref> <ref>PMID:15681610</ref> <ref>PMID:17084365</ref> <ref>PMID:20705812</ref> <ref>PMID:20929775</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Forneris F]] | |||
[[Category: Forneris | [[Category: Mattevi A]] | ||
[[Category: Mattevi | [[Category: Musacchio A]] | ||
[[Category: Musacchio | [[Category: Tortorci M]] | ||
[[Category: Tortorci | [[Category: Villa F]] | ||
[[Category: Villa | |||
