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==Crystal structure of LkcE E64Q mutant in complex with LC-KA05==
==Crystal structure of LkcE E64Q mutant in complex with LC-KA05==
<StructureSection load='6f7v' size='340' side='right' caption='[[6f7v]], [[Resolution|resolution]] 3.03&Aring;' scene=''>
<StructureSection load='6f7v' size='340' side='right'caption='[[6f7v]], [[Resolution|resolution]] 3.03&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6f7v]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"streptomyces_rochei_var._volubilis"_higashide_et_al._1971 "streptomyces rochei var. volubilis" higashide et al. 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F7V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F7V FirstGlance]. <br>
<table><tr><td colspan='2'>[[6f7v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_rochei_subsp._volubilis Streptomyces rochei subsp. volubilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F7V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6F7V FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CWH:[(2~{S},5~{R},8~{S},11~{S})-1-[(2~{R},3~{R},5~{R},6~{S})-3,5-dimethyl-6-oxidanyl-4-oxidanylidene-oxan-2-yl]-5,11-dimethyl-8-oxidanyl-13-[[(2~{S})-2-oxidanylpropanoyl]amino]tridecan-2-yl]+ethanoate'>CWH</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.03&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6f32|6f32]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CWH:[(2~{S},5~{R},8~{S},11~{S})-1-[(2~{R},3~{R},5~{R},6~{S})-3,5-dimethyl-6-oxidanyl-4-oxidanylidene-oxan-2-yl]-5,11-dimeth+yl-8-oxidanyl-13-[[(2~{S})-2-oxidanylpropanoyl]amino]tridecan-2-yl]+ethanoate'>CWH</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lkcE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=885435 "Streptomyces rochei var. volubilis" Higashide et al. 1971])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6f7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f7v OCA], [https://pdbe.org/6f7v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6f7v RCSB], [https://www.ebi.ac.uk/pdbsum/6f7v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6f7v ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Monoamine_oxidase Monoamine oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.4 1.4.3.4] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f7v OCA], [http://pdbe.org/6f7v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f7v RCSB], [http://www.ebi.ac.uk/pdbsum/6f7v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f7v ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/G4V2H3_STRRO G4V2H3_STRRO]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Streptomyces rochei var. volubilis higashide et al. 1971]]
[[Category: Large Structures]]
[[Category: Monoamine oxidase]]
[[Category: Streptomyces rochei subsp. volubilis]]
[[Category: Chagot, B]]
[[Category: Chagot B]]
[[Category: Collin, S]]
[[Category: Collin S]]
[[Category: Dorival, J]]
[[Category: Dorival J]]
[[Category: Drager, G]]
[[Category: Drager G]]
[[Category: Gruez, A]]
[[Category: Gruez A]]
[[Category: Jacob, C]]
[[Category: Jacob C]]
[[Category: Kirschning, A]]
[[Category: Kirschning A]]
[[Category: Paris, C]]
[[Category: Paris C]]
[[Category: Risser, F]]
[[Category: Risser F]]
[[Category: Weissman, K J]]
[[Category: Weissman KJ]]
[[Category: Amine oxydase]]
[[Category: Cyclase]]
[[Category: Flavoprotein]]
[[Category: Post-pks enzyme]]
[[Category: Tayloring enzyme]]
Retrieved from "https://proteopedia.org/6f7v"